On request here is how to set the profile option value using PL/SQL

Function FND_PROFILE.SAVE can be used to set the value of any profile option at any level i.e. Site, Application, Responsibility, User etc.

Below is a sample code of how to use this function

DECLARE
   a   BOOLEAN;
BEGIN
   a := fnd_profile.SAVE (‘CONC_REPORT_ACCESS_LEVEL’
                        , ‘R’
                        , ‘USER’
                        , ‘22746’
                        , NULL
                        , NULL
                         );
   IF a
   THEN
      DBMS_OUTPUT.put_line (‘Success’);
      COMMIT;
   ELSE
      DBMS_OUTPUT.put_line (‘Error’);
   END IF;
END;

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